氯化亚砜

氯化亚砜用途

【用途一】
用于医药、农药及染料等行业，主要用于生产水胺硫磷、速灭杀丁、克螨特驱虫净、消炎痛、维生素A等
【用途二】
用作有机合成的氯化剂，如醇类羟基的氯化、羧酸的氯化、酸酐的氯化、有机磺酸或硝基化合物的氯置换。制造酰基氯化物。制造医药中间体，例如驱虫净、无味合霉素。还用作脱水剂和溶剂。
【用途三】
主要用于制造酰基氯化物，还用于农药、医药、染料等的生产。

氯化亚砜名称

[ CAS 号 ]:
7719-09-7

[ 中文名 ]:
氯化亚砜

[ 英文名 ]:
Thionyl chloride

[中文别名 ]:

[英文别名 ]:

sulfonylchloride
MFCD00011449
Thionyl chloride
Sulfurous oxychloride
Sulfinyl chloride
sulfurous dichloride
Thionyl chloride [UN1836] [Corrosive]
EINECS 231-748-8
SOCl2
Thionyl dichloride

氯化亚砜物理化学性质

[ 密度 ]:
2.0±0.1 g/cm3

[ 沸点 ]:
79.0±9.0 °C at 760 mmHg

[ 熔点 ]:
-105 °C

[ 分子式 ]:
Cl₂OS

[ 分子量 ]:
118.970

[ 闪点 ]:
105°C

[ 精确质量 ]:
117.904694

[ PSA ]:
36.28000

[ LogP ]:
0.68

[ 外观性状 ]:
透明至黄色液体

[ 蒸汽压 ]:
100.3±0.1 mmHg at 25°C

[ 折射率 ]:
1.593

[ 储存条件 ]:
库房通风低温干燥,与碱类、食品添加剂分开存放

[ 稳定性 ]:
Reacts violently with water. Incompatible with most common metals, strong reducing agents, strong bases, alcohols, amines.

[ 水溶解性 ]:
REACTS

氯化亚砜MSDS

氯化亚砜毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XM5150000

CHEMICAL NAME :: Thionyl chloride

CAS REGISTRY NUMBER :: 7719-09-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: Cl2-O-S

MOLECULAR WEIGHT :: 118.96

WISWESSER LINE NOTATION :: OSGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ppm/1H

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A148-952 *** REVIEWS *** ACGIH TLV-CL 4.9 mg/m3 (1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1 ppm (5 mg/m3) JAN 1993 OEL-BELGIUM:STEL 1 ppm (4.9 mg/m3) JAN 1993 OEL-DENMARK:TWA 1 ppm (5 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (5 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 1 ppm (5 mg/m3) JAN 1993 OEL-UNITED KINGDOM:STEL 1 ppm (5 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO THIONYL CHLORIDE-air:CL 1 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82024 No. of Facilities: 73 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 2440 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82024 No. of Facilities: 43 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 7082 (estimated) No. of Female Employees: 1223 (estimated)

氯化亚砜安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H314-H331

[ 补充危害声明 ]:
Contact with water liberates toxic gas., Reacts violently with water.

[ 警示性声明 ]:
P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233

[ 靶器官 ]:
Blood, Central nervous system, Liver

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R14;R20/22;R29;R35

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S28-S27

[ 危险品运输编码 ]:
UN 1836 8/PG 1

[ WGK德国 ]:
1

[ RTECS号 ]:
XM5150000

[ 包装等级 ]:
I

[ 危险类别 ]:
8

[ 海关编码 ]:
2812101000

氯化亚砜合成路线

氯化亚砜上下游产品

氯化亚砜上游产品

氯化亚砜下游产品

氯化亚砜制备

1.氯磺酸法先将硫黄粉加入反应器中，通入氯气进行反应生成一氯化硫。再将一定量的氯磺酸和一氯化硫加入反应器内，在50℃以下通入氯气进行反应，反应好的物料经粗馏、冷凝，收集130℃以下的料液送至精馏锅，为了使低沸点的二氯化硫转变成一氯化硫留在锅内，则要加入粗品数量的15%～20%硫黄，然后送去精馏，经回流4h，色泽正常后，收集气相75～80℃的馏分，制得亚硫酰氯成品。其反应方程式如下：

2.二氧化硫法以硫黄、液氯和液体二氧化硫为原料，采用全循环和液相循环法，生产高纯度氯化亚砜矾，纯度99%以上，该方法工艺先进，产品质量稳定，“三废”排放少。

图XVI-4 制备SOCL2的制备

二氯亚砜也叫亚硫酰二氯或氯化亚硫酰。

图制备SOCl2的装置

1—烧瓶1；2—烧瓶2；3—密封磨口

(1).在如图所示的烧瓶1中加入纯净的发烟硫酸，在烧瓶2中加入SCl2。慢慢加热烧瓶1，并用冰水冷却烧瓶2，SO3进入SCl2中即开始发生反应，放出的SO2通过通风柜排出。当反应完成后将1拆除并密封磨口3，在隔绝湿气的条件下慢慢进行蒸馏。然后在中间馏分中加入硫，仔细地分馏数次。获取76～77℃完全无色的馏分为最后产品。

(2).用一装有回流冷凝管的250mL双口烧瓶作反应器，反应器经彻底干燥后放入100g PCl5。冷凝管的上端联接一支CaCl2干燥管，在反应器的另一口中插入一根导气管至瓶底。从导气管中通入经仔细干燥过的SO2气体，摇荡反应瓶以加速反应进行。数小时后，PCl5全部溶解，反应即完成。用高效能的分馏柱仔细分馏产物数次，可得SOCl2产品。

精制方法：工业品的亚硫酸（二）氯中常含有硫酰氯、一氯化硫和二氯化硫等杂质，一般重蒸一次即可使用，但仍带有黄色。若需高纯度的产品，可将450mL亚硫酰（二）氯与12.5g硫加热回流4.5小时，然后用高效分馏柱分馏两次可得无色纯品。也可在亚磷酸三苯酯存在下进行蒸馏精制。

3.在干燥的五氯化磷中通入干燥的二氧化硫气体，在搅拌下边回流边反应，反应放出的热量将五氯化磷熔融：

待五氯化磷完全熔融后，加热混合物并搅拌均匀。然后精馏混合物数次，收集77～80℃馏分，即得试剂氯化亚砜。

氯化亚砜海关

[ 海关编码 ]: 2812101000

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