2,4-二氯苯甲酸

2,4-二氯苯甲酸用途

【用途一】
用作医药、染料、农药中间体
【用途二】
用于染料制造及有机合成
【用途三】
2，4-二氯苯甲酸是杀菌剂啶斑肟的中间体，也是除草剂苄草唑和吡唑特的中间体。
【用途四】
可用作染料、杀菌剂、药物的中间体。用于抗疟药盐酸阿的平、非汞利尿药速尿的生产。
【用途五】
药物、染料和杀菌剂等的中间体。用于抗疟药盐酸阿的平、非汞利尿药速尿的生产。

2,4-二氯苯甲酸名称

[ CAS 号 ]:
50-84-0

[ 中文名 ]:
2,4-二氯苯甲酸

[ 英文名 ]:
2,4-Dichlorobenzoic acid

[中文别名 ]:

2,4-二氯安息香酸

[英文别名 ]:

2,4-Dichlorbenzoic acid
Benzoic acid, 2,4-dichloro-
2,4-Dichlorobenzoic acid
MFCD00002414
EINECS 200-067-8

2,4-二氯苯甲酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
309.5±22.0 °C at 760 mmHg

[ 熔点 ]:
157-160 °C(lit.)

[ 分子式 ]:
C₇H₄Cl₂O₂

[ 分子量 ]:
191.012

[ 闪点 ]:
141.0±22.3 °C

[ 精确质量 ]:
189.958832

[ PSA ]:
37.30000

[ LogP ]:
2.81

[ 外观性状 ]:
淡黄色粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.599

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
0.36 g/L (15 ºC)

2,4-二氯苯甲酸MSDS

2,4-二氯苯甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG6650000

CHEMICAL NAME :: Benzoic acid, 2,4-dichloro-

CAS REGISTRY NUMBER :: 50-84-0

BEILSTEIN REFERENCE NO. :: 1868192

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H4-Cl2-O2

MOLECULAR WEIGHT :: 191.01

WISWESSER LINE NOTATION :: QVR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1538,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 830 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: SKEZAP Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. (Nippon Shokuhin Eisei Gakkai c/o Shokuhin Eisei Senta, 2-6-1 Jingumae, Shibuya-ku, Tokyo 150, Japan) V.1- 1960- Volume(issue)/page/year: 20,332,1979

2,4-二氯苯甲酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39-S22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DG6650000

[ 海关编码 ]:
2916399090

2,4-二氯苯甲酸合成路线

2,4-二氯苯甲酸上下游产品

2,4-二氯苯甲酸上游产品

2,4-二氯苯甲酸下游产品

2,4-二氯苯甲酸制备

2,4-二氯苯甲酸海关

[ 海关编码 ]: 2916399090

[ 中文概述 ]:
2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2,4-二氯苯甲酸文献

Ambigol C and 2,4-dichlorobenzoic acid, natural products produced by the terrestrial cyanobacterium Fischerella ambigua.

J. Nat. Prod. 68 , 459-61, (2005)

The new natural products 3,5-bis(2,4-dichlorophenoxy)-2,6-dichlorophenol (ambigol C, 1), a highly chlorinated aromatic compound, and 2,4-dichlorobenzoic acid (2) were isolated from the terrestrial cya...

NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

J. Bacteriol. 178(9) , 2656-61, (1996)

Corynebacterium sepedonicum KZ-4, described earlier as a strain capable of growth on 2,4-dichlorobenzoate (G.M. Zaitsev and Y.N. Karasevich, Mikrobiologiya 54:356-369, 1985), is known to metabolize th...

Automated dynamic liquid-liquid-liquid microextraction followed by high-performance liquid chromatography-ultraviolet detection for the determination of phenoxy acid herbicides in environmental waters.

J. Chromatogr. A. 1082(2) , 121-7, (2005)

Automated dynamic liquid-liquid-liquid microextraction (D-LLLME) controlled by a programmable syringe pump and combined with HPLC-UV was investigated for the extraction and determination of 5 phenoxy ...

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