2-羟基-4-甲氧基苯甲醛

2-羟基-4-甲氧基苯甲醛用途

2-Hydroxy-4-methoxybenzaldehyde是香兰素的异构体,可用于合成尿苷M7。2-Hydroxy-4-methoxybenzaldehyd 是一种有效的酪氨酸酶 (tyrosinase) 抑制剂,来自三种东非药用植物,Mondia whitei、 Rhus vulgaris Meikle 和 Sclerocarya caffra Sond。

2-羟基-4-甲氧基苯甲醛名称

[ CAS 号 ]:
673-22-3

[ 中文名 ]:
2-羟基-4-甲氧基苯甲醛

[ 英文名 ]:
2-Hydroxy-4-methoxybenzaldehyde

[中文别名 ]:

[英文别名 ]:

o-Hydroxy-p-methoxybenzaldehyde
VHR BQ DO1
2-HO-4-MeO-C6H3CHO
2-Hydroxy-4-methoxybenzaldehyde
4-Methoxysalicylaldehyde
4-Methoxysalicyaldehyde
Salicylaldehyde, 4-methoxy-
Benzaldehyde,2-hydroxy-4-methoxy
2-Hydroxy-p-anisaldehyde
Benzaldehyde, 2-hydroxy-4-methoxy-

2-羟基-4-甲氧基苯甲醛生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 代谢酶/蛋白酶 >> 酪氨酸酶

[ 靶点 ]

Tyrosinase[2].

[参考文献]

[1]. Bodwell Graham, et al. An Inverse Electron-Demand Diels-Alder-Based Total Synthesis of Urolithin M7. Synlett. 2011 (15): 2245.

[2]. Kubo I, et al. 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants. Planta Med. 1999 Feb;65(1):19-22.

2-羟基-4-甲氧基苯甲醛物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
271.5±20.0 °C at 760 mmHg

[ 熔点 ]:
41-43 °C(lit.)

[ 分子式 ]:
C₈H₈O₃

[ 分子量 ]:
152.15

[ 闪点 ]:
112.1±15.3 °C

[ 精确质量 ]:
152.047348

[ PSA ]:
46.53000

[ LogP ]:
1.79

[ 外观性状 ]:
无色针状晶体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.588

[ 储存条件 ]:
室温

2-羟基-4-甲氧基苯甲醛MSDS

2-羟基-4-甲氧基苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ2810000

CHEMICAL NAME :: p-Anisaldehyde, 2-hydroxy-

CAS REGISTRY NUMBER :: 673-22-3

BEILSTEIN REFERENCE NO. :: 1072443

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H8-O3

MOLECULAR WEIGHT :: 152.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

2-羟基-4-甲氧基苯甲醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
BZ2810000

[ 海关编码 ]:
29124900

2-羟基-4-甲氧基苯甲醛合成路线

2-羟基-4-甲氧基苯甲醛上下游产品

2-羟基-4-甲氧基苯甲醛上游产品

2-羟基-4-甲氧基苯甲醛下游产品

2-羟基-4-甲氧基苯甲醛海关

[ 海关编码 ]: 2912499000

[ 中文概述 ]:
2912499000. 其他醛醚、醛酚及含其他含氧基的醛. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

2-羟基-4-甲氧基苯甲醛文献

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