萜品油烯

萜品油烯用途

Terpinolene 是一种能从多种芳香植物的精油中分离得到的天然单萜,具有抗增殖和/或细胞毒性特性。Terpinolene 有效抑制 N2a 神经母细胞瘤的增殖,并增加原代大鼠神经元的总抗氧化能力 (TAC)。Terpinolene 还有潜在镇静作用。

萜品油烯名称

[ CAS 号 ]:
586-62-9

[ 中文名 ]:
萜品油烯

[ 英文名 ]:
Terpinolene

[中文别名 ]:

[英文别名 ]:

4-Isopropylidene-1-methyl-cyclohexene
terpineoyl glucoside
4-Isopropylidéne-1-méthylcyclohexène
EINECS 205-341-0
1-Methyl-4-(2-propanyliden)cyclohexen
(±)-α-Terpinyl acetate
4,5-epoxy-p-menth-1-ene
1-methyl-4-(propan-2-ylidene)cyclohexene
MFCD00049191
para-menthadiene

萜品油烯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Aydin E, et al.Anticancer and antioxidant properties of terpinolene in rat brain cells. Arh Hig Rada Toksikol. 2013 Sep;64(3):415-24.

[2]. Ito K, et al.The sedative effect of inhaled terpinolene in mice and its structure-activity relationships. J Nat Med. 2013 Oct;67(4):833-7.

萜品油烯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
182.0±15.0 °C at 760 mmHg

[ 分子式 ]:
C₁₀H₁₆

[ 分子量 ]:
136.234

[ 闪点 ]:
64.4±0.0 °C

[ 精确质量 ]:
136.125198

[ LogP ]:
4.67

[ 外观性状 ]:
水白色至淡琥珀色液体，松木的气味

[ 蒸汽密度 ]:
~4.7 (vs air)

[ 蒸汽压 ]:
1.1±0.2 mmHg at 25°C

[ 折射率 ]:
1.481

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运

[ 水溶解性 ]:
水溶性：不溶；可溶于：醇,苯,乙醚

萜品油烯MSDS

萜品油烯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WZ6870000

CHEMICAL NAME :: Terpinolene

CAS REGISTRY NUMBER :: 586-62-9

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4390 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,877,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84513 No. of Facilities: 192 (estimated) No. of Industries: 7 No. of Occupations: 14 No. of Employees: 3815 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84513 No. of Facilities: 7432 (estimated) No. of Industries: 79 No. of Occupations: 65 No. of Employees: 141447 (estimated) No. of Female Employees: 40571 (estimated)

萜品油烯安全信息

[ 符号 ]:

GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H304-H317-H410

[ 警示性声明 ]:
P280-P301 + P310-P331

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
N

[ 风险声明 (欧洲) ]:
R50/53

[ 安全声明 (欧洲) ]:
S60-S61-S24/25-S22-S23

[ 危险品运输编码 ]:
UN 2541 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
WZ6870000

[ 包装等级 ]:
III

[ 危险类别 ]:
3.2

[ 海关编码 ]:
2902199090

萜品油烯合成路线

萜品油烯上下游产品

萜品油烯上游产品

萜品油烯下游产品

萜品油烯制备

生产方法：
由蒎烯经硫酸乙醇溶液处理而得。

萜品油烯海关

[ 海关编码 ]: 2902199090

[ 中文概述 ]:
2902199090 其他环烷烃、环烯烃及环萜烯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:2.0%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量

[ Summary ]:
2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

萜品油烯文献

Phytochemical analysis and in vitro biological activity of three Hypericum species from the Canary Islands (Hypericum reflexum, Hypericum canariense and Hypericum grandifolium).

Fitoterapia 100 , 95-109, (2015)

In the present work we carried out a phytochemical and biological investigation on three Hypericum species, i.e. Hypericum reflexum, Hypericum canariense and Hypericum grandifolium, from the Canary Is...

Eating Quality of Carrots (Daucus carota L.) Grown in One Conventional and Three Organic Cropping Systems over Three Years.

J. Agric. Food Chem. 63 , 9803-11, (2015)

The eating quality of carrots (Daucus carota L.) was investigated to evaluate the impact of cropping systems (one conventional and three organic systems) and growing years (2007, 2008, and 2009) on ro...

Fumigant toxicity and acetylcholinesterase inhibitory activity of 4 Asteraceae plant essential oils and their constituents against Japanese termite (Reticulitermes speratus Kolbe).

Pestic. Biochem. Physiol. 113 , 55-61, (2014)

This study investigated the fumigant toxicity of 4 Asteraceae plant essential oils and their constituents against the Japanese termite Reticulitermes speratus Kolbe. Fumigant toxicity varied with plan...

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