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6-氨基烟酸

6-氨基烟酸用途

6-氨基烟酸是GABAA受体激动剂,Ki值为4.4 nM[1]。

6-氨基烟酸名称

[ CAS 号 ]:
3167-49-5

[ 中文名 ]:
6-氨基烟酸

[ 英文名 ]:
6-Aminonicotinic acid

[中文别名 ]:

[英文别名 ]:

5-carboxy-2-aminopyridine
6-Aminonicotinicacid
6-Imino-1,6-dihydro-3-pyridinecarboxylic acid
3-Pyridinecarboxylic acid, 6-amino-
6-aminopyridine-3-carboxylic acid
Nicotinic acid,6-amino
2-amino-5-carboxypyridine
EINECS 221-630-4
Cinchomeronic acid
3-Pyridinecarboxylic acid, 1,6-dihydro-6-imino-

6-氨基烟酸生物活性

[ 描述 ]:

6-氨基烟酸是GABAA受体激动剂,Ki值为4.4 nM[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 跨膜转运 >> GABA受体

信号通路 >> 神经信号通路 >> GABA受体

6-氨基烟酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
222.6±50.0 °C at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₆H₆N₂O₂

[ 分子量 ]:
138.124

[ 闪点 ]:
88.4±30.1 °C

[ 精确质量 ]:
138.042923

[ PSA ]:
76.21000

[ LogP ]:
-0.74

[ 外观性状 ]:
淡黄色结晶

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.630

[ 储存条件 ]:
室温

[ 水溶解性 ]:
ca 1.0 g/L (20 ºC)

6-氨基烟酸MSDS

6-氨基烟酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi,T

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933399090

6-氨基烟酸合成路线

6-氨基烟酸上下游产品

6-氨基烟酸上游产品

6-氨基烟酸下游产品

6-氨基烟酸海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-氨基烟酸文献

Two genetically distinct pathways for transcriptional regulation of anaerobic gene expression in Salmonella typhimurium.

J. Bacteriol. 168(1) , 389-97, (1986)

Expression of the tripeptide permease gene tppB is anaerobically induced. This induction is independent of the fnr (oxrA) gene product, which is known to be required for the anaerobic induction of sev...

NAD metabolism in Salmonella typhimurium: isolation of pyridine analogue supersensitive (pas) and pas suppressor mutants.

J. Gen. Microbiol. 130(11) , 2873-81, (1984)

Mutants of Salmonella typhimurium supersensitive to the nicotinic acid analogue 6-amino-nicotinic acid (6ANA) were isolated as unable to grow on what are normally subinhibitory concentrations of the a...

Electrocatalytic synthesis of 6-aminonicotinic acid at silver cathodes under mild conditions. Gennaro A, et al.

Electrochem. Commun. 6(7) , 627-31, (2004)

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