钾离子荧光探针

钾离子荧光探针用途

PBFI-AM是测定细胞内K+含量的有用工具【1】。

钾离子荧光探针名称

[ CAS 号 ]:
124549-23-1

[ 中文名 ]:
钾离子荧光探针

[ 英文名 ]:
PBFI-AM

[英文别名 ]:

钾离子荧光探针生物活性

[ 描述 ]:

PBFI-AM是测定细胞内K+含量的有用工具【1】。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 跨膜转运 >> 钾通道

[参考文献]

[1]. B Andersson, et al. Induction of apoptosis by intracellular potassium ion depletion: using the fluorescent dye PBFI in a 96-well plate method in cultured lung cancer cells. Toxicol In Vitro. 2006 Sep;20(6):986-94.

钾离子荧光探针物理化学性质

[ 密度 ]:
1.295g/cm3

[ 沸点 ]:
1136.6ºC at 760 mmHg

[ 分子式 ]:
C₅₈H₆₂N₂O₂₄

[ 分子量 ]:
1171.11

[ 闪点 ]:
641.2ºC

[ 精确质量 ]:
1170.37000

[ PSA ]:
298.54000

[ LogP ]:
6.76280

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.559

[ 储存条件 ]:
2-8°C

钾离子荧光探针MSDS

详细MSDS(安全技术说明书)

钾离子荧光探针安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

钾离子荧光探针文献

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

PLoS ONE 7(8) , e43950, (2012)

Increasing evidence supports a critical role of T cells in neurodegeneration associated with acute and subacute brain inflammatory disorders. Granzyme B (GrB), released by activated T cells, is a cyto...

Fluorescent indicators for cytosolic sodium.

J. Biol. Chem. 264 , 19449, (1989)

Fluorescent indicators sensitive to cytosolic concentrations of free Na+ have been synthesized and characterized. They consist of a crown ether, 1,7-diaza-4,10,13-trioxacyclopentadecane, linked via it...

P. Jezek et al.

J. Biol. Chem. 264 , 10522, (1990)

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