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紫丁香酚甙; 刺五加甙B

紫丁香酚甙; 刺五加甙B用途

Syringin 是 Acanthopanax senticosus 中主要的一种生物活性酚苷类物质,具有抗骨质疏松的作用。Syringin 通过抑制自噬来防止压力超载引起的心肌肥厚。

紫丁香酚甙; 刺五加甙B名称

[ CAS 号 ]:
118-34-3

[ 中文名 ]:
刺五加苷

[ 英文名 ]:
Syringin

[中文别名 ]:

[英文别名 ]:

Sinapyl 4-O-β-D-glucopyranoside alcohol
MFCD00016778
Eleutheroside B
Ligustrin
Syringin
LILACIN
Sinapyl alcohol 4-O-glucoside
Methoxyconiferine

紫丁香酚甙; 刺五加甙B生物活性

[ 描述 ]:

Syringin 是 Acanthopanax senticosus 中主要的一种生物活性酚苷类物质,具有抗骨质疏松的作用。Syringin 通过抑制自噬来防止压力超载引起的心肌肥厚。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 自噬 >> 自噬

[参考文献]

[1]. Liu J, et al. Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT. Phytomedicine. 2018 Mar 15;42:43-50.

[2]. Li F, et al. Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy. Int J Mol Med. 2017 Jan;39(1):199-207.

紫丁香酚甙; 刺五加甙B物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
642.6±55.0 °C at 760 mmHg

[ 熔点 ]:
192°C

[ 分子式 ]:
C₁₇H₂₄O₉

[ 分子量 ]:
372.367

[ 闪点 ]:
342.4±31.5 °C

[ 精确质量 ]:
372.142029

[ PSA ]:
138.07000

[ LogP ]:
-1.94

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.623

[ 储存条件 ]:
2-8°C

紫丁香酚甙; 刺五加甙B安全信息

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2932999099

紫丁香酚甙; 刺五加甙B合成路线

详细合成路线

紫丁香酚甙; 刺五加甙B上下游产品

紫丁香酚甙; 刺五加甙B上游产品

紫丁香酚甙; 刺五加甙B下游产品

紫丁香酚甙; 刺五加甙B海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

紫丁香酚甙; 刺五加甙B文献

[Simultaneous determination of five glycosides in Aidi injection by RP-HPLC-ELSD].

Zhongguo Zhong Yao Za Zhi 36(6) , 706-8, (2011)

To develop a RP-HPLC-ELSD method for the simultaneous determination of five glycosides in Aidi injection.The separation was carried out at 35 degrees C on a Kromasil C18 column (4.6 mm x 250 mm, 5 mic...

Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons.

J. Nat. Med. 65(3-4) , 417-23, (2011)

Not only neuronal death but also neuritic atrophy and synaptic loss underlie the pathogenesis of Alzheimer's disease as direct causes of the memory deficit. Extracts of Siberian ginseng (the rhizome o...

[Chemical constituents from Exochorda racemosa].

Zhongguo Zhong Yao Za Zhi 36(9) , 1198-201, (2011)

To study the chemical constituents of Exochorda racemosa.Compounds were isolated and purified by silica gel, Sephadex LH-20, MCI gel and RP-18 column chromatography, and their structures were determin...

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