乙酸异丁酯

乙酸异丁酯用途

【用途一】
主要用作硝基漆和过氯乙烯漆的稀释剂，也可用作溶剂，还可作为塑料印花浆的稀释剂、制药行业的萃取剂等
【用途二】
GB 2760一96规定为允许使用的食用香料。主要用以配制香蕉、树莓、草莓和奶油等型香精。
【用途三】
硝化纤维及漆类的溶剂。该品具有生梨和复盆子的香气，常作果实香精，用于调配香蕉、菠萝、复盆子和梨味香精。也用作玫瑰的调配剂。
【用途四】
有机溶剂、硝化纤维及漆的溶剂、萃取剂、脱水剂。用火棉胶、硝化纤维、清漆、人造革、医药、塑料以及香料工业中。

乙酸异丁酯名称

[ CAS 号 ]:
110-19-0

[ 中文名 ]:
乙酸异丁酯

[ 英文名 ]:
Isobutyl acetate

[中文别名 ]:

[英文别名 ]:

Isobutyl ester of acetic acid
UNII-7CR47FO6LF
Isobutyl acetate
β -methylpropyl ethanoate
β-Methylpropyl ethanoate
Acetic Acid Isobutyl Ester
2-methylpropyl ethanoate
isobutyl ethanoate
MFCD00008932
2-methylpropyl acetate

乙酸异丁酯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
116.6±0.0 °C at 760 mmHg

[ 熔点 ]:
-99 °C

[ 分子式 ]:
C₆H₁₂O₂

[ 分子量 ]:
116.158

[ 闪点 ]:
21.7±0.0 °C

[ 精确质量 ]:
116.083733

[ PSA ]:
26.30000

[ LogP ]:
1.59

[ 外观性状 ]:
透明液体

[ 蒸汽密度 ]:
>4 (vs air)

[ 蒸汽压 ]:
18.0±0.2 mmHg at 25°C

[ 折射率 ]:
1.396

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放

[ 水溶解性 ]:
7 g/L (20 ºC)

乙酸异丁酯MSDS

详细MSDS(安全技术说明书)

乙酸异丁酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI4025000

CHEMICAL NAME :: Acetic acid, isobutyl ester

CAS REGISTRY NUMBER :: 110-19-0

BEILSTEIN REFERENCE NO. :: 1741909

LAST UPDATED :: 199712

DATA ITEMS CITED :: 31

MOLECULAR FORMULA :: C6-H12-O2

MOLECULAR WEIGHT :: 116.18

WISWESSER LINE NOTATION :: 1Y1&1OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,795,1978

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,795,1978 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,8,1974

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4763 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 41,31,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >17400 mg/kg

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,8,1974 *** REVIEWS *** ACGIH TLV-TWA 713 mg/m3 (150 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 150 ppm (700 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,139,1971 OSHA PEL (Gen Indu):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 150 ppm (700 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 150 ppm (700 mg/m3);STEL 187 ppm (875 mg/m3) JAN 1993 OEL-BELGIUM:TWA 150 ppm (713 mg/m3);STEL 187 ppm (888 mg/m3) JAN 1993 OEL-DENMARK:TWA 150 ppm (710 mg/m3) JAN 1993 OEL-FRANCE:TWA 150 ppm (710 mg/m3);STEL 200 ppm (940 mg/m3) JAN 1993 OEL-GERMANY:TWA 200 ppm (950 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 150 ppm (700 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 150 ppm (700 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 150 ppm (700 mg/m3);STEL 300 ppm JAN 1993 OEL-UNITED KINGDOM:TWA 150 ppm (700 mg/m3);STEL 187 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ISOBUTYL ACETATE-air:10H TWA 150 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 40410 No. of Facilities: 16707 (estimated) No. of Industries: 150 No. of Occupations: 81 No. of Employees: 85472 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 40410 No. of Facilities: 11899 (estimated) No. of Industries: 113 No. of Occupations: 78 No. of Employees: 160286 (estimated) No. of Female Employees: 41243 (estimated)

乙酸异丁酯安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H336

[ 补充危害声明 ]:
Repeated exposure may cause skin dryness or cracking.

[ 警示性声明 ]:
P210-P370 + P378-P403 + P235

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F

[ 风险声明 (欧洲) ]:
R11;R66

[ 安全声明 (欧洲) ]:
S16-S23-S25-S29-S33

[ 危险品运输编码 ]:
UN 1213 3/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
AI4025000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2915390090

乙酸异丁酯合成路线

详细合成路线

乙酸异丁酯上下游产品

乙酸异丁酯上游产品

乙酸异丁酯下游产品

乙酸异丁酯制备

1.由异丁醇与乙酐在硫酸存在下酯化而得。将乙酐和异丁醇混合后滴加硫酸，稍冷后加热回流5-6h，回流液用水洗2-3次，用碳酸钠中和，用水洗至中性，用氯化钙干燥，在油浴上减压分馏即得成品。

精制方法：所含杂质除水、乙酸和异丁醇外，尚含有同系物的异松体混合物。精制时用碳酸氢钠或碳酸钠饱和水溶液中和、洗涤，再用氯化钠饱和水溶液充分洗涤，无水硫酸钠或硫酸镁干燥后精馏。

2.制法：

过氧三氟乙酸溶液的制备：于盛有50mL二氯甲烷的反应瓶中，加入90%的H2O28.2mL（0.3mol），冷却下慢慢滴加三氟乙酸酐50.8mL（0.36mol）。加完后充分搅拌备用。于装有搅拌器、滴液漏斗、回流冷凝器的反应瓶中，加入130g干燥、研细的磷酸氢二钠，150mL二氯甲烷合甲基异丁基酮（2）20.0g（0.2mol），搅拌下于20min内滴加上述过氧三氟乙酸溶液，滴加过程中反应放热，剧烈回流。加完后继续加热回流反应30min。冷后，滤去不溶性的盐，并用二氯甲烷洗涤。合并滤液和洗涤液，用10%的碳酸钠溶液洗涤，无水硫酸钠干燥。常压蒸出大部分溶剂后，于装有分馏头的分馏装置中分馏，控制回流比，收集114～115.5℃的馏分，得无色透明液体（1）19.5g，收率84%。

乙酸异丁酯海关

[ 海关编码 ]: 2915390090

[ 中文概述 ]:
2915390090. 其他乙酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

乙酸异丁酯文献

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Appl. Microbiol. Biotechnol. 99(5) , 2291-304, (2015)

Volatile compounds produced by yeast during fermentation greatly influence the organoleptic qualities of wine. We developed a model to predict the combined effects of initial nitrogen and phytosterol ...

How do esters and dimethyl sulphide concentrations affect fruity aroma perception of red wine? Demonstration by dynamic sensory profile evaluation.

Food Chem. 194 , 196-200, (2015)

Our study focused on variations in wine aroma perception and molecular composition during tasting over a period of 30min. In parallel, dynamic analytical and sensory methods were applied to study chan...

Differentiation of South American crack and domestic (US) crack cocaine via headspace-gas chromatography/mass spectrometry.

Drug Test. Anal. 7(3) , 241-6, (2015)

South American 'crack' cocaine, produced directly from coca leaf, can be distinguished from US domestically produced crack on the basis of occluded solvent profiles. In addition, analysis of domestica...

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