Nucleic acid related compounds. 42. A general procedure for the efficient deoxygenation of secondary alcohols. Regiospecific and stereoselective conversion of …
MJ Robins, JS Wilson, F Hansske
文献索引：Robins; Wilson; Hansske Journal of the American Chemical Society, 1983 , vol. 105, # 12 p. 4059 - 4065
Abstract: Treatment of unhindered secondary alcohols with phenoxythiocarbonyl chloride (phenyl chlorothionocarbonate) in pyridine/dichloromethane, or in acetonitrile with 4- dimethylaminopyridine catalysis for hindered alcohols, gave clean conversion to their O- phenoxythiocarbonyl derivatives. Reductive deoxygenation of these phenyl thionocarbonate esters proceeded smoothly, using tri-n-butyltin hydride and a free radical initiator in warm ...
![4-amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile结构式](https://image.chemsrc.com/caspic/179/15676-19-4.png)
