Tetrahedron

Efficient esterification of carboxylic acids and phosphonic acids with trialkyl orthoacetate in ionic liquid

T Yoshino, S Imori, H Togo

文献索引：Yoshino, Tomonori; Imori, Satomi; Togo, Hideo Tetrahedron, 2006 , vol. 62, # 6 p. 1309 - 1317

被引用次数: 60

摘要

An operationally simple, inexpensive, efficient, and environmentally friendly esterification of various carboxylic acids, phosphonic acids, and phosphinic acids with triethyl orthoacetate or trimethyl orthoacetate under neutral conditions in a typical room temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate, was successfully carried out to provide the corresponding ethyl esters or methyl esters in high yields.

~97%

~87%

~94%

~95%

~92%

~10%

~98%

~96%

~98%

~90%

~94%

~80%

~91%

~96%

~97%

~51%

~91%

~90%

~73%

~10%

~91%

~90%

~98%

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