Specificity of creatine kinase. New glycocyamines and glycocyamine analogs related to creatine

GL Rowley, AL Greenleaf…

文献索引：Rowley,G.L. et al. Journal of the American Chemical Society, 1971 , vol. 93, p. 5542 - 5551

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被引用次数: 114

摘要

Abstract: The specificity of rabbit muscle creatine kinase (adenosine triphosphate-creatine phosphotransferase, EC 2.7. 3.2) for a series of new synthetic analogs of creatine has been investigated. Two of these analogs, 1-car-boxymethyl-2-iminoimidazolidine and N-methyl-N- amidinoaminomethylphosphinic acid, are more reactive (31 and 13 as reactive as creatine, respectively) as substrates in the creatine kinase reaction than any analogs of creatine ...