Non??Racemic Halohydrins via Biocatalytic Hydrogen??Transfer Reduction of Halo??Ketones and One??Pot Cascade Reaction to Enantiopure Epoxides

TM Poessl, B Kosjek, U Ellmer…

文献索引：Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1827 - 1834

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被引用次数: 56

摘要

... Keywords: asymmetric synthesis; cascade reaction; enzyme catalysis; epoxides; halohydrins; hydrogen- transfer reduction ... and 1-chloro-1-phenyl-2-prop- anone (6a),[29] were synthesized as described ... Upscaled Chemoenzymatic “one-Pot” Synthesis of (R)-1,2-Epoxyoctane (1c ...