Tetrahedron: Asymmetry

Two step synthesis of C 2 symmetric 2, 6-diaryl-alkyloxybenzaldehydes—a mitsunobu approach

JRL Smith, P O'Brien, G Reginato

文献索引：Smith, John R. Lindsay; O'Brien, Peter; Reginato, Gloriana Tetrahedron Asymmetry, 1997 , vol. 8, # 20 p. 3415 - 3420

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被引用次数: 9

摘要

A simple two step method for the synthesis of three novel C2 symmetric 2, 6- diarylalkyloxybenzaldehydes is described. Starting from resorcinol, the route involves double Mitsunobu reaction with chiral alcohols followed by regiospecific lithiation and formylation.