Water Accessibility to the Binding Cleft as a Major Switching Factor from Entropy??Driven to Enthalpy??Driven Binding of an Alkyl Group by Synthetic Receptors
S Matsumoto, H Iwamoto…
文献索引：Matsumoto, Sayaka; Iwamoto, Hiroya; Mizutani, Tadashi Chemistry - An Asian Journal, 2010 , vol. 5, # 5 p. 1163 - 1170
Abstract Free energy, enthalpy, and entropy changes in the binding of alkyl pyridines to water-soluble zinc porphyrin receptors with varying accessibility of water to the binding cleft were determined to explain why the driving force of hydrophobic effects is enthalpic in some occasions and entropic in others. Zinc porphyrins bearing four alkyl pillars with terminal solubilizing poly (oxyethylene)(POE) chains of molecular weight of 750 (1), with eight alkyl ...
