Tetrahedron Letters

o-Quinone methide based approach to isoflavans: application to the total syntheses of equol, 3′-hydroxyequol and vestitol

…, AM Sathiyanarayanan, P Jonnalagadda

文献索引：Gharpure, Santosh J.; Sathiyanarayanan; Jonnalagadda, Prasad Tetrahedron Letters, 2008 , vol. 49, # 18 p. 2974 - 2978

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被引用次数: 32

摘要

A concise strategy is developed for the synthesis of isoflavans employing a Diels–Alder reaction between o-quinone methides and aryl-substituted enol ethers followed by reductive cleavage of the acetal group. The method is extended towards the total syntheses of equol, 3′-hydroxyequol and vestitol.