Rhodium-catalyzed anti-Markovnikov intermolecular hydroalkoxylation of terminal acetylenes

M Kondo, T Kochi, F Kakiuchi

文献索引：Kondo, Masataka; Kochi, Takuya; Kakiuchi, Fumitoshi Journal of the American Chemical Society, 2011 , vol. 133, # 1 p. 32 - 34

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被引用次数: 35

摘要

We report here the first transition-metal-catalyzed anti-Markovnikov intermolecular hydroalkoxylation of terminal acetylenes to give enol ethers in high yields without using bases. Arylacetylenes as well as alkenyl-and alkylacetylenes were coupled with aliphatic alcohols, and the products were obtained with high Z selectivity in most cases. Effective catalysts were 8-quinolinolato rhodium complexes, which are structurally simple but have ...