Tetrahedron

Aprotic diazotization in the presence of cuprous cyanide

AG Giumanini, G Verardo, P Geatti, P Strazzolini

文献索引：Giumanini, Angelo G.; Verardo, Giancarlo; Geatti, Paola; Strazzolini, Paolo Tetrahedron, 1996 , vol. 52, # 20 p. 7137 - 7148

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被引用次数: 10

摘要

In a procedure of extreme simplicity and rapidity a mixture of an aromatic primary amine, copper (I) cyanide and an alkyl nitrite in dimethyl sulphoxide yielded fair to moderate yields of the corresponding nitriles. Side processes observed were reduction (NH2→ H), nitration (NH2→ NO2) and hydroxylation (NH2→ OH). In the case of polyhaloanilines halogen dance products could be detected.