前往化源商城

European Journal of Organic Chemistry

Stereoselective Olefination of N??Sulfonyl Imines with Stabilized Phosphonium Ylides for the Synthesis of Electron??Deficient Alkenes

F Fang, Y Li, SK Tian

文献索引:Fang, Fan; Li, Yuan; Tian, Shi-Kai European Journal of Organic Chemistry, 2011 , # 6 p. 1084 - 1091

全文:HTML全文

被引用次数: 21

摘要

Abstract An unprecedented protocol has been developed for thestereoselective synthesis of structurally diverse electron-deficient alkenes in moderate to excellent yields from readily accessible N-sulfonyl imines and stabilized phosphonium ylides. Significantly, the olefination reaction of N-sulfonylimines with nitrile-stabilized phosphonium ylides affords an array of α, β-unsaturated nitriles with high Z selectivity, and the reactions with ester-, ...

 相关合成线路

~90%

~83%

~98%

~99%

~10%

~99%

~84%

~59%

~%

~78%

~98%

~0%

~76%

~0%

详细

~74%

~27%

~%

~%

~%

~%

~86%

~99%

~%

~%

~%

~%

~%

~%

~%

~%

~81%

~54%