European Journal of Organic Chemistry

Stereoselective Olefination of N??Sulfonyl Imines with Stabilized Phosphonium Ylides for the Synthesis of Electron??Deficient Alkenes

F Fang, Y Li, SK Tian

Index: Fang, Fan; Li, Yuan; Tian, Shi-Kai European Journal of Organic Chemistry, 2011 , # 6 p. 1084 - 1091

Full Text: HTML

Citation Number: 21

Abstract

Abstract An unprecedented protocol has been developed for thestereoselective synthesis of structurally diverse electron-deficient alkenes in moderate to excellent yields from readily accessible N-sulfonyl imines and stabilized phosphonium ylides. Significantly, the olefination reaction of N-sulfonylimines with nitrile-stabilized phosphonium ylides affords an array of α, β-unsaturated nitriles with high Z selectivity, and the reactions with ester-, ...

 Related Synthetic Route

~90%

Learn More

~83%

Learn More

~98%

Learn More

~99%

Learn More

~10%

Learn More

~99%

Learn More

~84%

Learn More

~59%

Learn More

~%

Learn More

~78%

Learn More

~98%

Learn More

~0%

Learn More

~76%

Learn More

~0%

Detail Learn More

~74%

Learn More

~27%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~86%

Learn More

~99%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~%

Learn More

~81%

Learn More

~54%

Learn More