Ethyl 4-methoxycinnamate

Modify Date: 2024-01-02 16:57:39

Ethyl 4-methoxycinnamate Structure
Ethyl 4-methoxycinnamate structure
Common Name Ethyl 4-methoxycinnamate
CAS Number 24393-56-4 Molecular Weight 206.238
Density 1.1±0.1 g/cm3 Boiling Point 325.1±17.0 °C at 760 mmHg
Molecular Formula C12H14O3 Melting Point 49ºC
MSDS Chinese USA Flash Point 133.8±15.5 °C

 Use of Ethyl 4-methoxycinnamate


(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM, respectively[1].

 Names

Name Ethyl 4-methoxycinnamate
Synonym More Synonyms

 Ethyl 4-methoxycinnamate Biological Activity

Description (E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM, respectively[1].
Related Catalog
Target

COX-1:1.12 μM (IC50)

COX-2:0.83 μM (IC50)

References

[1]. Umar MI, et al. Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galangal L. extracts. Molecules. 2012 Jul 23;17(7):8720-34.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 325.1±17.0 °C at 760 mmHg
Melting Point 49ºC
Molecular Formula C12H14O3
Molecular Weight 206.238
Flash Point 133.8±15.5 °C
Exact Mass 206.094299
PSA 35.53000
LogP 2.65
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.540

 Safety Information

Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-Propenoic acid, 3-(4-methoxyphenyl)-, ethyl ester, (2E)-
Ferulic acid,ethyl ester
4-Methoxycinnamic Acid Ethyl Ester
ethyl p-methoxycinnamate
3-(4-Methoxyphenyl)acrylic Acid Ethyl Ester
Ethyl (2E)-3-(4-methoxyphenyl)-2-propenoate
Ethyl 4'-hydroxy-3'-methoxycinnamate
p-Methoxycinnamic acid ethyl ester
(E)-Ethyl 3-(4-methoxyphenyl)acrylate
Ethyl 4-MethoxycinnaMate
2-Propenoic acid, 3-(4-methoxyphenyl)-, ethyl ester
ethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
Ethyl trans-4-methoxycinnamate
Ethyl (2E)-3-(4-methoxyphenyl)acrylate
ethyl ferulate
Ethyl 3-(4-methoxyphenyl)-2-propenoate
Ethyl 3-(4-Methoxyphenyl)acrylate
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