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24393-56-4

24393-56-4 structure
24393-56-4 structure

Name Ethyl 4-methoxycinnamate
Synonyms 2-Propenoic acid, 3-(4-methoxyphenyl)-, ethyl ester, (2E)-
Ferulic acid,ethyl ester
4-Methoxycinnamic Acid Ethyl Ester
ethyl p-methoxycinnamate
3-(4-Methoxyphenyl)acrylic Acid Ethyl Ester
Ethyl (2E)-3-(4-methoxyphenyl)-2-propenoate
Ethyl 4'-hydroxy-3'-methoxycinnamate
p-Methoxycinnamic acid ethyl ester
(E)-Ethyl 3-(4-methoxyphenyl)acrylate
Ethyl 4-MethoxycinnaMate
2-Propenoic acid, 3-(4-methoxyphenyl)-, ethyl ester
ethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate
Ethyl trans-4-methoxycinnamate
Ethyl (2E)-3-(4-methoxyphenyl)acrylate
ethyl ferulate
Ethyl 3-(4-methoxyphenyl)-2-propenoate
Ethyl 3-(4-Methoxyphenyl)acrylate
Description (E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM, respectively[1].
Related Catalog
Target

COX-1:1.12 μM (IC50)

COX-2:0.83 μM (IC50)

References

[1]. Umar MI, et al. Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galangal L. extracts. Molecules. 2012 Jul 23;17(7):8720-34.

Density 1.1±0.1 g/cm3
Boiling Point 325.1±17.0 °C at 760 mmHg
Melting Point 49ºC
Molecular Formula C12H14O3
Molecular Weight 206.238
Flash Point 133.8±15.5 °C
Exact Mass 206.094299
PSA 35.53000
LogP 2.65
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.540
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%