Bioorganic & medicinal chemistry

Synthesis of quercetin glycosides and their melanogenesis stimulatory activity in B16 melanoma cells

K Yamauchi, T Mitsunaga, I Batubara

文献索引：Yamauchi, Kosei; Mitsunaga, Tohru; Batubara, Irmanida Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 937 - 944

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被引用次数: 12

摘要

Abstract 4′-O-β-d-Glucopyranosyl-quercetin-3-O-β-d-glucopyranosyl-(1→ 4)-β-d-glucopyra- noside (3) was isolated from Helminthostachys zeylanica root extract as a melanogenesis acceleration compound and was synthesized using rutin as the starting material. Related compounds were also synthesized to understand the structure–activity relationships in melanin biosynthesis.