Tetrahedron Letters

Regio-and stereoselective synthesis of the major metabolite of quercetin, quercetin-3-O-β-d-glucuronide

M Bouktaib, A Atmani, C Rolando

文献索引：Bouktaib, Mohamed; Atmani, Aziz; Rolando, Christian Tetrahedron Letters, 2002 , vol. 43, # 35 p. 6263 - 6266

全文：HTML全文

被引用次数: 99

摘要

Protected quercetin was first transformed selectively in its 3-O-β-d-glucoside. Further protection of the remaining phenolic hydroxyl group allows a clean oxidation of the glucoside by TEMPO/NaOCl/NaBr under phase transfer conditions into the corresponding glucuronide which was cleanly deprotected to quercetin-3-O-β-d-glucuronide.