H-Gly-Pro-OH

Names

[ CAS No. ]:
704-15-4

[ Name ]:
H-Gly-Pro-OH

[Synonym ]:
MFCD00020840
Glycyl-L-proline
1-glycyl-L-Proline
Proline, 1-glycyl-, L-
L-Proline, glycyl-
(2S)-1-(Aminoacetyl)-2-pyrrolidinecarboxylic acid
1-Glycyl-L-prolin
Gly-l-pro
L-Proline, 1-glycyl-
EINECS 211-880-2
H-Gly-Pro-OH

Biological Activity

[Description]:

H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Le J, et al. Urine glycyl-L-proline increase and skin trophicity. Amino Acids. 1999;17(3):315-22.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
411.3±40.0 °C at 760 mmHg

[ Melting Point ]:
185℃

[ Molecular Formula ]:
C₇H₁₂N₂O₃

[ Molecular Weight ]:
172.182

[ Flash Point ]:
202.6±27.3 °C

[ Exact Mass ]:
172.084793

[ PSA ]:
83.63000

[ LogP ]:
-1.34

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.557

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

J. Chromatogr. A. 562(1-2) , 125-38, (1991)

Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...

Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.

Anal. Chem. 83(7) , 2705-11, (2011)

Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few inter...

Diagnostic use of cerebral and extracerebral oxysterols.

Clin. Chem. Lab Med. 42(2) , 186-91, (2004)

24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed t...