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NT 13

Names

[ CAS No. ]:
117928-93-5

[ Name ]:
NT 13

[Synonym ]:
threonylprolylprolylthreonine
(2S,3R)-2-({(S)-1-[(S)-1-((2S,3R)-2-Amino-3-hydroxy-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonyl}-amino)-3-hydroxy-butyric acid
NT 13

Biological Activity

[Description]:

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Peptides

[Target]

Target: NMDAR[1]


[In Vitro]

NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist[1].

[References]

[1]. Moskal J. Methods of treating depression and other related diseases. US9340576B2


[Related Small Molecules]

(+)-MK 801 Maleate | CNQX | N-Methyl-D-aspartic acid | ifenprodil tartrate | D-AP5(mM/ml) | DNQX | Ro 25-6981 maleate | Flupirtine maleate | Mibampator | CX546 | Naspm | Talampanel | Centrophenoxine hydrochloride | 24-Hydroxycholesterol

Chemical & Physical Properties

[ Molecular Formula ]:
C18H30N4O7

[ Molecular Weight ]:
414.45300

[ Exact Mass ]:
414.21100

[ PSA ]:
173.50000

[ Storage condition ]:
2-8℃

Related Compounds

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