117928-93-5
117928-93-5 structure
- Name: NT 13
- Chemical Name: Thr-Pro-Pro-Thr
- CAS Number: 117928-93-5
- Molecular Formula: C18H30N4O7
- Molecular Weight: 414.45300
- Catalog: Peptides
- Create Date: 2018-05-12 21:13:47
- Modify Date: 2025-08-25 07:44:25
-
NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.
| Name | Thr-Pro-Pro-Thr |
|---|---|
| Synonyms |
threonylprolylprolylthreonine
(2S,3R)-2-({(S)-1-[(S)-1-((2S,3R)-2-Amino-3-hydroxy-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonyl}-amino)-3-hydroxy-butyric acid NT 13 |
| Description | NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases. |
|---|---|
| Related Catalog | |
| Target |
Target: NMDAR[1] |
| In Vitro | NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist[1]. |
| References |
[1]. Moskal J. Methods of treating depression and other related diseases. US9340576B2 |
| Molecular Formula | C18H30N4O7 |
|---|---|
| Molecular Weight | 414.45300 |
| Exact Mass | 414.21100 |
| PSA | 173.50000 |
| Storage condition | 2-8℃ |