CLK1/2-IN-1

Names

[ CAS No. ]:
1005784-23-5

[ Name ]:
CLK1/2-IN-1

Biological Activity

[Description]:

CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CLK1:16 nM (IC50)

CLK2:45 nM (IC50)


[References]

[1]. Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One

Chemical & Physical Properties

[ Molecular Formula ]:
C21H20F3N7O

[ Molecular Weight ]:
443.43

Related Compounds