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L-香芹酮

L-香芹酮用途

Carvone 是一种酮单萜,主要存在于薄荷属植物的精油中。Carvone 广泛应用于制药工业、化妆品和农业。Carvone 具有抗菌、抗氧化、抗炎、解痉、镇痛、抗惊厥等作用。

L-香芹酮名称

[ CAS 号 ]:
99-49-0

[ 中文名 ]:
香芹酮

[ 英文名 ]:
DL-carvone

[中文别名 ]:

[英文别名 ]:

Carvone
2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-on
5-Isopropenyl-2-methyl-2-cyclohexen-1-one
2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-enone
EINECS 202-759-5
2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-
(RS)-p-mentha-6,8-dien-2-one
2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one
2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one
(RS)-5-isopropenyl-2-methylcyclohex-2-en-1-one

L-香芹酮生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

研究领域 >> 炎症/免疫

研究领域 >> 神经疾病

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Lícia T S Pina, et al. Carvone and its pharmacological activities: A systematic review. Phytochemistry. 2022 Apr:196:113080.

L-香芹酮物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
230.5±35.0 °C at 760 mmHg

[ 熔点 ]:
230℃

[ 分子式 ]:
C₁₀H₁₄O

[ 分子量 ]:
150.218

[ 闪点 ]:
88.9±0.0 °C

[ 精确质量 ]:
150.104462

[ PSA ]:
17.07000

[ LogP ]:
2.27

[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C

[ 折射率 ]:
1.481

[ 储存条件 ]:
2-8°C，干燥，密封

L-香芹酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OS8575000

CHEMICAL NAME :: p-Mentha-6,8-dien-2-one

CAS REGISTRY NUMBER :: 99-49-0

BEILSTEIN REFERENCE NO. :: 1364206

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H14-O

MOLECULAR WEIGHT :: 150.24

WISWESSER LINE NOTATION :: L6V BUTJ B1 EY1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1640 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2675 mg/kg

TOXIC EFFECTS :: Behavioral - anticonvulsant Behavioral - sleep

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,77,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 766 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964

L-香芹酮安全信息

[ 危害码 (欧洲) ]:
Xn

L-香芹酮合成路线

详细合成路线

L-香芹酮上下游产品

L-香芹酮上游产品

L-香芹酮下游产品

L-香芹酮制备

1.L-型香芹酮可以由留兰香精油中分离制得， D-型香芹酮可由黄蒿油中分离制得。