<生产厂家价格>

棕榈酰甘氨酸

棕榈酰甘氨酸用途

棕榈酰甘氨酸是一种新型的内源性脂质,在感觉神经元中作为钙内流和一氧化氮生成的调节剂。棕榈酰甘氨酸通过钙敏感型一氧化氮合酶诱导短暂的钙内流,然后产生一氧化氮。棕榈酰甘氨酸可有效抑制大鼠背角痛觉神经元的热诱发放电【1】。

棕榈酰甘氨酸名称

[ CAS 号 ]:
2441-41-0

[ 中文名 ]:
棕榈酰甘氨酸

[ 英文名 ]:
PALGLY

[英文别名 ]:

N-Ethanoyl-Hexadecanamide
PALGLY
N-hexadecanoyl glycine
Palmitoylglycine
QV1MV15
N-palmitatoylglycyne
N-(1-Oxohexadecyl)glycine
N-Hexadecanoylglycine
Glycine, N-(1-oxohexadecyl)-
Hexadecanoylaminoacetic acid N-palmitoyl glycine

棕榈酰甘氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> 钙通道

信号通路 >> 免疫及炎症 >> 一氧化氮合酶

研究领域 >> 神经疾病

[参考文献]

[1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24.

棕榈酰甘氨酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
491.8±28.0 °C at 760 mmHg

[ 分子式 ]:
C₁₈H₃₅NO₃

[ 分子量 ]:
313.48

[ 闪点 ]:
251.2±24.0 °C

[ 精确质量 ]:
313.261688

[ PSA ]:
66.40000

[ LogP ]:
6.03

[ 外观性状 ]:
white to off-white

[ 蒸汽压 ]:
0.0±2.7 mmHg at 25°C

[ 折射率 ]:
1.468

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
DMSO: >10mg/mL

棕榈酰甘氨酸MSDS

棕榈酰甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2924199090

棕榈酰甘氨酸合成路线

棕榈酰甘氨酸上下游产品

棕榈酰甘氨酸上游产品

棕榈酰甘氨酸下游产品

棕榈酰甘氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

棕榈酰甘氨酸文献

¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.

PLoS ONE 10(3) , e0120950, (2015)

Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information of curcumin on hyperlipidemia models has been...

GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.

PLoS ONE 8 , e60314, (2013)

The G-protein coupled receptor 55 (GPR55) is activated by lysophosphatidylinositols and some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/inflammatory pain, cancer and b...

Glycine N-acyltransferase-like 3 is responsible for long-chain N-acylglycine formation in N18TG2 cells.

J. Lipid Res. 57 , 781-90, (2016)

Long-chain fatty acid amides are signaling lipids found in mammals and other organisms; however, details of the metabolic pathways for the N-acylglycines and primary fatty acid amides (PFAMs) have rem...

更多文献