α,β-亚甲基腺苷 5'-二磷酸 钠盐

更新时间:2024-01-16 14:01:08

α,β-亚甲基腺苷 5'-二磷酸 钠盐结构式
α,β-亚甲基腺苷 5'-二磷酸 钠盐结构式
品牌特惠专场
常用名 α,β-亚甲基腺苷 5'-二磷酸 钠盐 英文名 ALPHA,BETA-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
CAS号 104835-70-3 分子量 469.19200
密度 N/A 沸点 N/A
分子式 C11H15N5Na2O9P2 熔点 N/A
MSDS 美版 闪点 N/A

 用途


αβ-亚甲基腺苷5′-二磷酸(AMP-CP)是ADP类似物,具有抑制胞外核苷酸酶/CD73 的能力,通过CD73/胞外-5′-核苷酸酶,用于研究腺苷能信号调控。

 名称

中文名 Α,Β-亚甲基腺苷 5'-二磷酸钠盐
英文名 α,β-METHYLENEADENOSINE 5'-DIPHOSPHATE SODIUM SALT
英文别名 更多

 物理化学性质

分子式 C11H15N5Na2O9P2
分子量 469.19200
精确质量 469.01400
PSA 248.65000
外观性状 固体
储存条件 20°C

 安全信息

危害码 (欧洲) Xi: Irritant;
风险声明 (欧洲) 36/37/38
安全声明 (欧洲) 26-36
危险品运输编码 NONH for all modes of transport

 文献4

更多文献
IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

Eur. J. Immunol. 38 , 2718-2726, (2008)

IFN-beta treatment reduces the relapse rate in MS but its mechanism of action remains incompletely understood. Our aim was to clarify the beneficial effect of IFN-beta in the treatment of MS. We asses...

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression.

Eur. J. Immunol. 41 , 1231-1241, (2011)

CD73/ecto-5'-nucleotidase dephosphorylates extracellular AMP into adenosine, and it is a key enzyme in the regulation of adenosinergic signaling. The contribution of host CD73 to tumor growth and anti...

Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells.

Pharmacology 84 , 196-202, (2009)

Extracellular ATP may be metabolized to AMP and adenosine by the ectonucleotidases CD39 and CD73 and, in this study, we characterized the pathways for adenosine formation in human urinary tract epithe...

 英文别名

AMP-CP SODIUM SALT
A,B-methyleneadenosine 5'-diphosphate*sodium