E3 ligase Ligand 9

Modify Date: 2024-01-10 13:27:05

E3 ligase Ligand 9 Structure
E3 ligase Ligand 9 structure
Common Name E3 ligase Ligand 9
CAS Number 87304-15-2 Molecular Weight 408.48900
Density N/A Boiling Point N/A
Molecular Formula C21H32N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of E3 ligase Ligand 9


E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

 Names

Name N-Boc bestatin
Synonym More Synonyms

 E3 ligase Ligand 9 Biological Activity

Description E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog
References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

 Chemical & Physical Properties

Molecular Formula C21H32N2O6
Molecular Weight 408.48900
Exact Mass 408.22600
PSA 124.96000
LogP 2.88060

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(S)-2-[(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
N-Boc-bestain
N-Boc Bestatin