AChE/BChE-IN-11

Modify Date: 2024-02-07 12:52:12

AChE/BChE-IN-11 Structure
AChE/BChE-IN-11 structure
Common Name AChE/BChE-IN-11
CAS Number 80443-12-5 Molecular Weight 466.39200
Density N/A Boiling Point N/A
Molecular Formula C21H22O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AChE/BChE-IN-11


AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].

 Names

Name (2R,3R)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one

 AChE/BChE-IN-11 Biological Activity

Description AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].
Related Catalog
Target

AChE:70 μM (IC50)

BChE:71 μM (IC50)

References

[1]. Elsebai MF, et, al. X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside. Sci Rep. 2022 Nov 1;12(1):18351.  

 Chemical & Physical Properties

Molecular Formula C21H22O12
Molecular Weight 466.39200
Exact Mass 466.11100
PSA 206.60000