ZP 120C

Modify Date: 2024-01-13 18:01:21

ZP 120C structure	Common Name	ZP 120C
	CAS Number	383123-18-0	Molecular Weight	1781.20
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₅HN₂₇O₁₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZP 120C

ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].

Name	ZP 120C

Description	ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	NOP Receptor/ORL1
In Vitro	ZP 120C (1 nM) inhibits electrically induced contraction of the mouse vas deferen[2]. ZP 120C (1 μM) inhibits electrical field stimulation (EFS)-induced contractions in rat arteries[3].
In Vivo	ZP 120C (1 nM/kg/min, i.v., 2.5 h) displays an aquaretic effect in conscious, chronically instrumented rats with congestive heart failure (CHF)[1] .ZP 120C (1 nM, i.c.v., 30 min) produces pronociceptive effects in the tail withdrawal assay and decreases locomotor activity in mice[2] . Animal Model: Rats induced by left coronary artery ligation (LCAL)[1] Dosage: 1 nM/kg/min Administration: Intravenous injection (i.v.), 2.5 h of constant intravenous infusion Result: Increased diuresis, free water clearance, fractional water excretion, and fractional distal water excretion.

Molecular Formula	C₈₅HN₂₇O₁₅
Molecular Weight	1781.20