383123-18-0

383123-18-0 structure
383123-18-0 structure
  • Name: ZP 120C
  • Chemical Name: ZP 120C
  • CAS Number: 383123-18-0
  • Molecular Formula: C85HN27O15
  • Molecular Weight: 1781.20
  • Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
  • Create Date: 2022-12-04 07:05:06
  • Modify Date: 2024-01-13 18:01:21
  • ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].

Name ZP 120C
Description ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].
Related Catalog
Target

NOP Receptor/ORL1

In Vitro ZP 120C (1 nM) inhibits electrically induced contraction of the mouse vas deferen[2]. ZP 120C (1 μM) inhibits electrical field stimulation (EFS)-induced contractions in rat arteries[3].
In Vivo ZP 120C (1 nM/kg/min, i.v., 2.5 h) displays an aquaretic effect in conscious, chronically instrumented rats with congestive heart failure (CHF)[1] .ZP 120C (1 nM, i.c.v., 30 min) produces pronociceptive effects in the tail withdrawal assay and decreases locomotor activity in mice[2] . Animal Model: Rats induced by left coronary artery ligation (LCAL)[1] Dosage: 1 nM/kg/min Administration: Intravenous injection (i.v.), 2.5 h of constant intravenous infusion Result: Increased diuresis, free water clearance, fractional water excretion, and fractional distal water excretion.
Molecular Formula C85HN27O15
Molecular Weight 1781.20