383123-18-0
383123-18-0 structure
- Name: ZP 120C
- Chemical Name: ZP 120C
- CAS Number: 383123-18-0
- Molecular Formula: C85HN27O15
- Molecular Weight: 1781.20
- Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
- Create Date: 2022-12-04 07:05:06
- Modify Date: 2025-08-23 08:36:01
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ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3].
| Name | ZP 120C |
|---|
| Description | ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia[1][3]. |
|---|---|
| Related Catalog | |
| Target |
NOP Receptor/ORL1 |
| In Vitro | ZP 120C (1 nM) inhibits electrically induced contraction of the mouse vas deferen[2]. ZP 120C (1 μM) inhibits electrical field stimulation (EFS)-induced contractions in rat arteries[3]. |
| In Vivo | ZP 120C (1 nM/kg/min, i.v., 2.5 h) displays an aquaretic effect in conscious, chronically instrumented rats with congestive heart failure (CHF)[1] .ZP 120C (1 nM, i.c.v., 30 min) produces pronociceptive effects in the tail withdrawal assay and decreases locomotor activity in mice[2] . Animal Model: Rats induced by left coronary artery ligation (LCAL)[1] Dosage: 1 nM/kg/min Administration: Intravenous injection (i.v.), 2.5 h of constant intravenous infusion Result: Increased diuresis, free water clearance, fractional water excretion, and fractional distal water excretion. |
| Molecular Formula | C85HN27O15 |
|---|---|
| Molecular Weight | 1781.20 |