EZH2-IN-9

Modify Date: 2024-04-09 13:53:43

EZH2-IN-9 Structure
EZH2-IN-9 structure
Common Name EZH2-IN-9
CAS Number 2700897-24-9 Molecular Weight 596.09
Density N/A Boiling Point N/A
Molecular Formula C28H32ClF2N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EZH2-IN-9


EZH2-IN-9 is a potent inhibitor of EZH2. EZH2 overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) all lead to abnormal elevation of H3K27me3 and promote the growth and development of many types of tumors, such as breast cancer, prostate cancer, leukemia, etc. EZH2-IN-9 has the potential for the research of cancer diseases (extracted from patent WO2021180235A1, compound 17)[1].

 Names

Name EZH2-IN-9

 EZH2-IN-9 Biological Activity

Description EZH2-IN-9 is a potent inhibitor of EZH2. EZH2 overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) all lead to abnormal elevation of H3K27me3 and promote the growth and development of many types of tumors, such as breast cancer, prostate cancer, leukemia, etc. EZH2-IN-9 has the potential for the research of cancer diseases (extracted from patent WO2021180235A1, compound 17)[1].
Related Catalog
References

[1]. Li Yao, et al. Zeste enhancer homologue 2 inhibitor and its use. Patent WO2021180235A1.

 Chemical & Physical Properties

Molecular Formula C28H32ClF2N3O5S
Molecular Weight 596.09