EZH2-IN-5
Modify Date: 2025-09-20 18:02:26
EZH2-IN-5 structure
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Common Name | EZH2-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 1403258-69-4 | Molecular Weight | 517.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H37BrN4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EZH2-IN-5EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1]. |
| Name | EZH2-IN-5 |
|---|
| Description | EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
EZH2 WT:1.52 nM (IC50) EZH2 Y641F mutant type:4.07 nM (IC50) |
| In Vitro | EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM[1]. |
| References |
[1]. Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1 |
| Molecular Formula | C26H37BrN4O2 |
|---|---|
| Molecular Weight | 517.50 |
| InChIKey | FKKHGOZTTQASQA-UHFFFAOYSA-N |
| SMILES | CCN(c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 |