Glucocorticoid receptor-IN-1
Modify Date: 2024-01-09 16:42:36
Glucocorticoid receptor-IN-1 structure
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Common Name | Glucocorticoid receptor-IN-1 | ||
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| CAS Number | 2662908-25-8 | Molecular Weight | 513.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H19F4N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Glucocorticoid receptor-IN-1Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1]. |
| Name | Glucocorticoid receptor-IN-1 |
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| Description | Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1]. |
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| Related Catalog | |
| In Vitro | Glucocorticoid receptor-IN-1 (Compound WX002) shows inhibitory effect on CYP3A4 with an IC50 of 16.7 µM[1]. |
| References |
[1]. Guoli Zhang, et al. Benzo[d][1,2,3]triazole ether compound. WO2021136431. |
| Molecular Formula | C24H19F4N7O2 |
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| Molecular Weight | 513.45 |