EZH2-IN-7

Modify Date: 2024-01-14 17:38:08

EZH2-IN-7 Structure
EZH2-IN-7 structure
Common Name EZH2-IN-7
CAS Number 2659225-28-0 Molecular Weight 563.75
Density N/A Boiling Point N/A
Molecular Formula C31H37D2N5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EZH2-IN-7


EZH2-IN-7 is a potent inhibitor of EZH2. EZH2 overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) all lead to abnormal elevation of H3K27me3 and promote the growth and development of many types of tumors, such as breast cancer, prostate cancer, leukemia, etc. EZH2-IN-7 has the potential for the research of cancer diseases (extracted from patent WO2021129629A1, compound 259)[1].

 Names

Name EZH2-IN-7

 EZH2-IN-7 Biological Activity

Description EZH2-IN-7 is a potent inhibitor of EZH2. EZH2 overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) all lead to abnormal elevation of H3K27me3 and promote the growth and development of many types of tumors, such as breast cancer, prostate cancer, leukemia, etc. EZH2-IN-7 has the potential for the research of cancer diseases (extracted from patent WO2021129629A1, compound 259)[1].
Related Catalog
References

[1]. Li Yao, et al. Zeste enhancer homologue 2 inhibitor and its use. Patent WO2021129629A1.

 Chemical & Physical Properties

Molecular Formula C31H37D2N5O3S
Molecular Weight 563.75