KSK67

Modify Date: 2024-01-13 16:16:10

KSK67 structure	Common Name	KSK67
	CAS Number	2566715-93-1	Molecular Weight	365.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₇N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KSK67

KSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain[1].

Name	KSK67

Description	KSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	3.2, 1531, 101 nM (H3 receptor, sigma-1, sigma-2 receptor)[1]
References	[1]. Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683.

Molecular Formula	C₂₂H₂₇N₃O₂
Molecular Weight	365.47

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KSK67

Use of KSK67

Names

KSK67 Biological Activity

Chemical & Physical Properties