PI3K/mTOR Inhibitor-7

Modify Date: 2024-01-05 17:48:32

PI3K/mTOR Inhibitor-7 structure	Common Name	PI3K/mTOR Inhibitor-7
	CAS Number	2456295-65-9	Molecular Weight	571.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₃N₉O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PI3K/mTOR Inhibitor-7

PI3K/mTOR Inhibitor-7 (Compound 19i) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-7 shows 4.7-fold higher potency than the positive control gedatolisib (0.3 vs. 1.4 μM, IC50 values). PI3K/mTOR Inhibitor-7 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-7 has the potential for the research of cancer diseases[1].

Name	PI3K/mTOR Inhibitor-7

Description	PI3K/mTOR Inhibitor-7 (Compound 19i) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-7 shows 4.7-fold higher potency than the positive control gedatolisib (0.3 vs. 1.4 μM, IC50 values). PI3K/mTOR Inhibitor-7 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-7 has the potential for the research of cancer diseases[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Wang L, et al. Design, synthesis and bioevaluation of novel substituted triazines as potential dual PI3K/mTOR inhibitors. Eur J Med Chem. 2020 Oct 15;204:112637

Molecular Formula	C₂₉H₃₃N₉O₄
Molecular Weight	571.63

PI3K/mTOR Inhibitor-7

Use of PI3K/mTOR Inhibitor-7

Names

PI3K/mTOR Inhibitor-7 Biological Activity

Chemical & Physical Properties