MAT2A-IN-3

Modify Date: 2024-01-08 19:12:46

MAT2A-IN-3 Structure
MAT2A-IN-3 structure
Common Name MAT2A-IN-3
CAS Number 2377493-28-0 Molecular Weight 517.41
Density N/A Boiling Point N/A
Molecular Formula C24H16F5N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAT2A-IN-3


MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265)[1].

 Names

Name MAT2A-IN-3

 MAT2A-IN-3 Biological Activity

Description MAT2A-IN-3 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-3 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has the potential for the research of cancer diseases (extracted from patent WO2019191470A1, compound 265)[1].
Related Catalog
References

[1]. Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2019191470A1.

 Chemical & Physical Properties

Molecular Formula C24H16F5N5O3
Molecular Weight 517.41