MLK-IN-1

Modify Date: 2024-01-04 16:12:07

MLK-IN-1 structure	Common Name	MLK-IN-1
	CAS Number	1627729-62-7	Molecular Weight	432.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MLK-IN-1

MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].

Name	MLK-IN-1

Description	MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> Mixed Lineage Kinase Research Areas >> Neurological Disease
Target	MLK3
In Vitro	MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].
References	[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.

Molecular Formula	C₂₃H₂₀N₄O₃S
Molecular Weight	432.49