MLK-IN-1

Names

[ Name ]:
MLK-IN-1

Biological Activity

[Description]:

MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> Mixed Lineage Kinase

Research Areas >> Neurological Disease

[Target]

MLK3

[In Vitro]

MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1].

[References]

[1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₀N₄O₃S

[ Molecular Weight ]:
432.49

Related Compounds

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