Propargyl-PEG5-azide

Modify Date: 2024-01-09 22:53:15

Propargyl-PEG5-azide structure	Common Name	Propargyl-PEG5-azide
	CAS Number	1589522-62-2	Molecular Weight	301.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₂₃N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-PEG5-azide

Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG5-azide

Description	Propargyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1012.

Molecular Formula	C₁₃H₂₃N₃O₅
Molecular Weight	301.34