RIPK1-IN-13

Modify Date: 2023-01-19 13:47:06

RIPK1-IN-13 structure	Common Name	RIPK1-IN-13
	CAS Number	1574547-67-3	Molecular Weight	397.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₀ClN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RIPK1-IN-13

RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].

Name	RIPK1-IN-13

Description	RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
References	[1]. Niu A, et al. Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors. Bioorg Med Chem. 2022 Apr 1;59:116686.

Molecular Formula	C₂₁H₂₀ClN₃O₃
Molecular Weight	397.85

RIPK1-IN-13

Use of RIPK1-IN-13

Names

RIPK1-IN-13 Biological Activity

Chemical & Physical Properties