RIPK1-IN-4

Modify Date: 2024-02-05 19:12:16

RIPK1-IN-4 structure	Common Name	RIPK1-IN-4
	CAS Number	1481641-08-0	Molecular Weight	401.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₃N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RIPK1-IN-4

RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase[1].

Name	RIPK1-IN-4

Description	RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
Target	IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)[1]
References	[1]. Harris PA, et al. Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis. ACS Med Chem Lett. 2013 Nov 4;4(12):1238-43.

Molecular Formula	C₂₃H₂₃N₅O₂
Molecular Weight	401.46

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: RIPK1-IN-4
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.