1574547-67-3

1574547-67-3 structure

Name: RIPK1-IN-13
Chemical Name: RIPK1-IN-13
CAS Number: 1574547-67-3
Molecular Formula: C₂₁H₂₀ClN₃O₃
Molecular Weight: 397.85
Catalog: Signaling Pathways Apoptosis RIP kinase
Create Date: 2022-07-11 17:02:41
Modify Date: 2025-08-29 21:22:34
RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].

Name	RIPK1-IN-13

Description	RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
References	[1]. Niu A, et al. Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors. Bioorg Med Chem. 2022 Apr 1;59:116686.

Molecular Formula	C₂₁H₂₀ClN₃O₃
Molecular Weight	397.85