m-PEG6-Hydrazide

Modify Date: 2024-01-10 13:11:15

m-PEG6-Hydrazide Structure
m-PEG6-Hydrazide structure
Common Name m-PEG6-Hydrazide
CAS Number 1449390-64-0 Molecular Weight 338.40
Density N/A Boiling Point N/A
Molecular Formula C14H30N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG6-Hydrazide


m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG6-Hydrazide

 m-PEG6-Hydrazide Biological Activity

Description m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C14H30N2O7
Molecular Weight 338.40