m-PEG6-thiol

Modify Date: 2024-01-04 21:31:00

m-PEG6-thiol Structure
m-PEG6-thiol structure
Common Name m-PEG6-thiol
CAS Number 441771-60-4 Molecular Weight 312.42300
Density 1.057 Boiling Point N/A
Molecular Formula C13H28O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG6-thiol


m-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG6-thiol Biological Activity

Description m-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.057
Molecular Formula C13H28O6S
Molecular Weight 312.42300
Exact Mass 312.16100
PSA 94.18000
LogP 0.64560

 Safety Information

Hazard Codes Xi

 Synonyms

3,6,9,12,15,18-hexaoxanonadecane-1-thiol
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  • DC Chemicals Limited
  • China
  • Product Name: m-PEG6-thiol
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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