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1644231-07-1

1644231-07-1 structure
1644231-07-1 structure
  • Name: m-PEG6-amino-Mal
  • Chemical Name: MPEG6-Mal
  • CAS Number: 1644231-07-1
  • Molecular Formula: C20H34N2O9
  • Molecular Weight: 446.492
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-08 21:56:48
  • Modify Date: 2025-08-27 10:04:13
  • m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name MPEG6-Mal
Synonyms 1H-Pyrrole-1-propanamide, N-3,6,9,12,15,18-hexaoxanonadec-1-yl-2,5-dihydro-2,5-dioxo-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17-hexaoxanonadecan-19-yl)propanamide
MFCD27977520
Description m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 604.5±55.0 °C at 760 mmHg
Molecular Formula C20H34N2O9
Molecular Weight 446.492
Flash Point 319.4±31.5 °C
Exact Mass 446.226440
LogP -2.78
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.493
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